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The occurrence of bone erosion during the progression of RA is closely related to the ROS-induced upregulation of nuclear factor of activated T cells 1 (NFATc1), a regulator of osteoclast activity and bone resorption in rats, which promotes RANKL-induced osteoclastogenesis and the differentiation of mouse bone marrow macrophages (BMMs) into osteoclasts

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VLPs, which mimic the structure and properties of viral particles, have shown promise in cancer immunotherapy as antigen-presenting platforms or carriers of immunostimulatory molecules (Shahrivarkevishahi et al., 2022)

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